Krister Wennerberg: search on Z-Library

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1

Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses

Varghese, Finny S., Kaukinen, Pasi, Gläsker, Sabine, Bespalov, Maxim, Hanski, Leena, Wennerberg, Krister, Kümmerer, Beate M., Ahola, Tero

Journal:

Antiviral Research

Year:

2016

Language:

english

File:

PDF, 1.55 MB

english, 2016

2

Network pharmacology applications to map the unexplored target space and therapeutic potential of natural products

Kibble, Milla, Saarinen, Niina, Tang, Jing, Wennerberg, Krister, Mäkelä, Sari, Aittokallio, Tero

Journal:

Natural Product Reports

Year:

2015

Language:

english

File:

PDF, 982 KB

english, 2015

3

KIT pathway upregulation predicts dasatinib efficacy in acute myeloid leukemia

Malani, Disha, Yadav, Bhagwan, Kumar, Ashwini, Potdar, Swapnil, Kontro, Mika, Kankainen, Matti, Javarappa, Komal K., Porkka, Kimmo, Wolf, Maija, Aittokallio, Tero, Wennerberg, Krister, Heckman, Caroli

Journal:

Year:

2020

File:

PDF, 644 KB

2020

4

Breeze: an integrated quality control and data analysis application for high-throughput drug screening

Potdar, Swapnil, Ianevski, Aleksandr, Mpindi, John-Patrick, Bychkov, Dmitrii, Fiere, ClÃ©ment, Ianevski, Philipp, Yadav, Bhagwan, Wennerberg, Krister, Aittokallio, Tero, Kallioniemi, Olli, Saarela, Ja

Journal:

Year:

2020

File:

PDF, 288 KB

2020

5

Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth

Al-Ali, Hassan, Lee, Do-Hun, Danzi, Matt C., Nassif, Houssam, Gautam, Prson, Wennerberg, Krister, Zuercher, Bill, Drewry, David H., Lee, Jae K., Lemmon, Vance P., Bixby, John L.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 4.09 MB

english, 2015

6

Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells

Gautam, Prson, Karhinen, Leena, Szwajda, Agnieszka, Jha, Sawan Kumar, Yadav, Bhagwan, Aittokallio, Tero, Wennerberg, Krister

Journal:

Molecular Cancer

Year:

2016

Language:

english

File:

PDF, 1.48 MB

english, 2016

7

A normalized drug response metric improves accuracy and consistency of anticancer drug sensitivity quantification in cell-based screening

Gupta, Abhishekh, Gautam, Prson, Wennerberg, Krister, Aittokallio, Tero

Journal:

Communications Biology

Year:

2020

Language:

english

File:

PDF, 1.19 MB

english, 2020

8

Rnd Proteins Function as RhoA Antagonists by Activating p190 RhoGAP

Krister Wennerberg, Marie-Annick Forget, Shawn M Ellerbroek, William T Arthur, Keith Burridge, Jeffrey Settleman, Channing J Der, Steen H Hansen

Journal:

Current Biology

Year:

2003

Language:

english

File:

PDF, 576 KB

english, 2003

9

Toward universal protein post-translational modification detection in high throughput format

Härmä, Harri, Tong-Ochoa, Natalia, van Adrichem, Arjan J., Jelesarov, Ilian, Wennerberg, Krister, Kopra, Kari

Journal:

Chemical Communications

Year:

2018

Language:

english

File:

PDF, 2.14 MB

english, 2018

10

Interactive visual analysis of drug–target interaction networks using Drug Target Profiler, with applications to precision medicine and drug repurposing

Tanoli, Ziaurrehman, Alam, Zaid, Ianevski, Aleksandr, Wennerberg, Krister, Vähä-Koskela, Markus, Aittokallio, Tero

Journal:

Briefings in Bioinformatics

Year:

2018

File:

PDF, 8.96 MB

2018

11

Prediction of drug combination effects with a minimal set of experiments

Ianevski, Aleksandr, Giri, Anil K., Gautam, Prson, Kononov, Alexander, Potdar, Swapnil, Saarela, Jani, Wennerberg, Krister, Aittokallio, Tero

Journal:

Nature Machine Intelligence

Year:

2019

File:

PDF, 2.07 MB

2019

12

Systematic Mapping of Kinase Addiction Combinations in Breast Cancer Cells by Integrating Drug Sensitivity and Selectivity Profiles

Szwajda, Agnieszka, Gautam, Prson, Karhinen, Leena, Jha, Sawan Kumar, Saarela, Jani, Shakyawar, Sushil, Turunen, Laura, Yadav, Bhagwan, Tang, Jing, Wennerberg, Krister, Aittokallio, Tero

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 3.71 MB

english, 2015

13

Genomic Perturbations Reveal Distinct Regulatory Networks in Intrahepatic Cholangiocarcinoma

Nepal, Chirag, O'Rourke, Colm J., Oliveira, Douglas VNP, Taranta, Andrzej, Shema, Steven, Gautam, Prson, Calderaro, Julien, Barbour, Andrew, Raggi, Chiara, Wennerberg, Krister, Wang, Xin W., Lautem, A

Journal:

Year:

2017

Language:

english

File:

PDF, 1.84 MB

english, 2017

14

Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein–Protein Interaction Data

Pokharel, Yuba Raj, Saarela, Jani, Szwajda, Agnieszka, Rupp, Christian, Rokka, Anne, Kumar Lal Karna, Shibendra, Teittinen, Kaisa, Corthals, Garry, Kallioniemi, Olli, Wennerberg, Krister, Aittokallio,

Journal:

Molecular & Cellular Proteomics

Year:

2015

Language:

english

File:

PDF, 1.66 MB

english, 2015

15

Impact of normalization methods on high-throughput screening data with high hit rates and drug testing with dose–response data

Mpindi, John-Patrick, Swapnil, Potdar, Dmitrii, Bychkov, Jani, Saarela, Saeed, Khalid, Wennerberg, Krister, Aittokallio, Tero, Östling, Päivi, Kallioniemi, Olli

Journal:

Year:

2015

Language:

english

File:

PDF, 849 KB

english, 2015

16

MgcRacGAP inhibition stimulates JAK-dependent STAT3 activity

van Adrichem, Arjan J., Wennerberg, Krister

Journal:

Year:

2015

Language:

english

File:

PDF, 1.30 MB

english, 2015

17

Patient-customized Drug Combination Prediction and Testing for T-cell Prolymphocytic Leukemia Patients

He, Liye, Tang, Jing, Andersson, Emma I, Timonen, Sanna, Koschmieder, Steffen, Wennerberg, Krister, Mustjoki, Satu, Aittokallio, Tero

Journal:

Cancer Research

Year:

2018

Language:

english

File:

PDF, 2.87 MB

english, 2018

18

Novel Screening Method Identifies PI3Kα, mTOR, and IGF1R as Key Kinases Regulating Cardiomyocyte Survival

Elmadani, Manar, Khan, Suleiman, Tenhunen, Olli, Magga, Johanna, Aittokallio, Tero, Wennerberg, Krister, Kerkelä, Risto

Journal:

Journal of the American Heart Association

Year:

2019

File:

PDF, 1.79 MB

2019

19

Pan-RAF inhibition induces apoptosis in acute myeloid leukemia cells and synergizes with BCL2 inhibition

Tambe, Mahesh, Karjalainen, Ella, VÃ¤hÃ¤-Koskela, Markus, Bulanova, Daria, Gjertsen, BjÃ¸rn T., Kontro, Mika, Porkka, Kimmo, Heckman, Caroline A., Wennerberg, Krister

Journal:

Year:

2020

File:

PDF, 1.07 MB

2020

20

Identification of novel small molecule activators of nuclear factor-κb with neuroprotective action via high-throughput screening

Marina S. Manuvakhova, Guyla G. Johnson, Misti C. White, Subramaniam Ananthan, Melinda Sosa, Clinton Maddox, Sara McKellip, Lynn Rasmussen, Krister Wennerberg, Judith V. Hobrath, E. Lucile White, Jose

Journal:

Journal of Neuroscience Research

Year:

2011

Language:

english

File:

PDF, 1.41 MB

english, 2011

21

Utilization of in situ ELISA method for examining Trk receptor phosphorylation in cultured cells

Antila, Hanna, Autio, Henri, Turunen, Laura, Harju, Kirsi, Tammela, Päivi, Wennerberg, Krister, Yli-Kauhaluoma, Jari, Huttunen, Henri J., Castrén, Eero, Rantamäki, Tomi

Journal:

Journal of Neuroscience Methods

Year:

2014

Language:

english

File:

PDF, 1023 KB

english, 2014

22

Global proteomics profiling improves drug sensitivity prediction: results from a multi-omics, pan-cancer modeling approach

Ali, Mehreen, Khan, Suleiman A, Wennerberg, Krister, Aittokallio, Tero

Journal:

Year:

2017

Language:

english

File:

PDF, 892 KB

english, 2017

23

Making Sense of Large-Scale Kinase Inhibitor Bioactivity Data Sets: A Comparative and Integrative Analysis

Tang, Jing, Szwajda, Agnieszka, Shakyawar, Sushil, Xu, Tao, Hintsanen, Petteri, Wennerberg, Krister, Aittokallio, Tero

Journal:

Journal of Chemical Information and Modeling

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

24

Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways

Tang, Jing, Karhinen, Leena, Xu, Tao, Szwajda, Agnieszka, Yadav, Bhagwan, Wennerberg, Krister, Aittokallio, Tero, Roth, Frederick P.

Journal:

PLoS Computational Biology

Year:

2013

Language:

english

File:

PDF, 1.27 MB

english, 2013

25

Therapeutic targeting of KSP in preclinical models of high-risk neuroblastoma

Hansson, Karin, Radke, Katarzyna, Aaltonen, Kristina, Saarela, Jani, MaÃ±as, Adriana, SjÃ¶lund, Jonas, Smith, Emma M., Pietras, Kristian, PÃ¥hlman, Sven, Wennerberg, Krister, Gisselsson, David, Bexell

Journal:

Science Translational Medicine

Year:

2020

File:

PDF, 3.54 MB

2020

26

Searching for Drug Synergy in Complex Dose–Response Landscapes Using an Interaction Potency Model

Yadav, Bhagwan, Wennerberg, Krister, Aittokallio, Tero, Tang, Jing

Journal:

Computational and Structural Biotechnology Journal

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015

27

Consistency in drug response profiling

Mpindi, John Patrick, Yadav, Bhagwan, Östling, Päivi, Gautam, Prson, Malani, Disha, Murumägi, Astrid, Hirasawa, Akira, Kangaspeska, Sara, Wennerberg, Krister, Kallioniemi, Olli, Aittokallio, Tero

Journal:

Year:

2016

Language:

english

File:

PDF, 690 KB

english, 2016

28

What is synergy? The Saariselkä agreement revisited

Tang, Jing, Wennerberg, Krister, Aittokallio, Tero

Journal:

Frontiers in Pharmacology

Year:

2015

Language:

english

File:

PDF, 404 KB

english, 2015

29

Drug screening approach combines epigenetic sensitization with immunochemotherapy in cancer

Facciotto, Chiara, Casado, Julia, Turunen, Laura, Leivonen, Suvi-Katri, Tumiati, Manuela, Rantanen, Ville, Kauppi, Liisa, Lehtonen, Rainer, Leppä, Sirpa, Wennerberg, Krister, Hautaniemi, Sampsa

Journal:

Clinical Epigenetics

Year:

2019

File:

PDF, 1.39 MB

2019

30

MLK3 Limits Activated Gαq Signaling to Rho by Binding to p63RhoGEF

Katherine I. Swenson-Fields, Joshua C. Sandquist, Jessica Rossol-Allison, Irene C. Blat, Krister Wennerberg, Keith Burridge, Anthony R. Means

Journal:

Year:

2008

Language:

english

File:

PDF, 1.52 MB

english, 2008

31

β1 Integrin-Dependent and -Independent Polymerization of Fibronectin

Krister Wennerberg, Lars Lohikangas, Donald Gullberg, Martin Pfaff, Staffan Johansson and Reinhard Fässler

Journal:

The Journal of Cell Biology

Year:

1996

Language:

english

File:

PDF, 5.59 MB

english, 1996

32

Integrin signaling to the actin cytoskeleton

Kris A DeMali, Krister Wennerberg, Keith Burridge

Journal:

Current Opinion in Cell Biology

Year:

2003

Language:

english

File:

PDF, 598 KB

english, 2003

33

Phenotypic Screening Combined with Machine Learning for Efficient Identification of Breast Cancer-Selective Therapeutic Targets

Gautam, Prson, Jaiswal, Alok, Aittokallio, Tero, Al-Ali, Hassan, Wennerberg, Krister

Journal:

Cell Chemical Biology

Year:

2019

Language:

english

File:

PDF, 2.57 MB

english, 2019

34

Systematic identification of feature combinations for predicting drug response with Bayesian multi-view multi-task linear regression

Ammad-ud-din, Muhammad, Khan, Suleiman A., Wennerberg, Krister, Aittokallio, Tero

Journal:

Year:

2017

Language:

english

File:

PDF, 5.17 MB

english, 2017

35

A High-Throughput Screen for Chemical Inhibitors of Exocytic Transport in Yeast

Lisha Zhang, N. Miranda Nebane, Krister Wennerberg , Yujie Li , Valerie Neubauer , Judith V. Hobrath, Sara McKellip, Lynn Rasmussen, Nice Shindo, Melinda Sosa, Joseph A. Maddry, Subramaniam Ananthan,

Journal:

Year:

2010

Language:

english

File:

PDF, 1.57 MB

english, 2010

36

Probabilistic toxicogenomics studies in vitro

Juuso Parkkinen, Rebecca Ceder, Egon Willighagen, Krister Wennerberg, Samuel Kaski, Roland Grafström

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 88 KB

english, 2012

37

Drug sensitivity testing on patient-derived sarcoma cells predicts patient response to treatment and identifies c-Sarc inhibitors as active drugs for translocation sarcomas

Brodin, Bertha A., Wennerberg, Krister, Lidbrink, Elisabet, Brosjö, Otte, Potdar, Swapnil, Wilson, Jennifer N., Ma, Limin, Moens, Lotte N., Hesla, Asle, Porovic, Edvin, Bernhardsson, Edvin, Papakonsta

Journal:

British Journal of Cancer

Year:

2019

Language:

english

File:

PDF, 1.34 MB

english, 2019

38

Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib

Dyczynski, Matheus, Yu, Yasmin, Otrocka, Magdalena, Parpal, Santiago, Braga, Tiago, Henley, Aine Brigette, Zazzi, Henric, Lerner, Mikael, Wennerberg, Krister, Viklund, Jenny, Martinsson, Jessica, Gran

Journal:

Year:

2018

Language:

english

File:

PDF, 1.11 MB

english, 2018

39

Identification of novel regulators of STAT3 activity

Parri, Elina, KuusanmÃ¤ki, Heikki, van Adrichem, Arjan J., Kaustio, Meri, Wennerberg, Krister, Datti, Alessandro

Journal:

Year:

2020

File:

PDF, 2.80 MB

2020

40

Comprehensive Drug Testing of Patient-derived Conditionally Reprogrammed Cells from Castration-resistant Prostate Cancer

Saeed, Khalid, Rahkama, Vesa, Eldfors, Samuli, Bychkov, Dmitry, Mpindi, John Patrick, Yadav, Bhagwan, Paavolainen, Lassi, Aittokallio, Tero, Heckman, Caroline, Wennerberg, Krister, Peehl, Donna M., Ho

Journal:

European Urology

Year:

2016

Language:

english

File:

PDF, 2.92 MB

english, 2016

41

Integrative and Personalized QSAR Analysis in Cancer by Kernelized Bayesian Matrix Factorization

Ammad-ud-din, Muhammad, Georgii, Elisabeth, Gönen, Mehmet, Laitinen, Tuomo, Kallioniemi, Olli, Wennerberg, Krister, Poso, Antti, Kaski, Samuel

Journal:

Journal of Chemical Information and Modeling

Year:

2014

Language:

english

File:

PDF, 4.41 MB

english, 2014

42

A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury

Kohonen, Pekka, Parkkinen, Juuso A., Willighagen, Egon L., Ceder, Rebecca, Wennerberg, Krister, Kaski, Samuel, Grafström, Roland C.

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 2.05 MB

english, 2017

43

A personalised medicine drug sensitivity and resistance testing platform and utilisation of acoustic droplet ejection at the Institute for Molecular Medicine Finland

Saarela, Jani, Kulesskiy, Evgeny, Laamanen, Karoliina, Pemovska, Tea, Pietiäinen, Vilja, Potdar, Swapnil, von Schantz-Fant, Carina, Turunen, Laura, Östling, Päivi, Wennerberg, Krister

Journal:

Year:

2014

Language:

english

File:

PDF, 216 KB

english, 2014

44

Phenotypic Screening Combined with Machine Learning for Efficient Identification of Breast Cancer-Selective Therapeutic Targets

Gautam, Prson, Jaiswal, Alok, Aittokallio, Tero, Al-Ali, Hassan, Wennerberg, Krister

Journal:

Cell Chemical Biology

Year:

2019

File:

PDF, 2.57 MB

2019

45

Cancer Cell Drug Response Transcriptomes in 3D

Wennerberg, Krister

Journal:

Cell Chemical Biology

Year:

2016

Language:

english

File:

PDF, 170 KB

english, 2016

46

Corrigendum to “Searching for drug synergy in complex dose–response landscapes using an interaction potency model” [Comput. Struct. Biotechnol. J. 13 (2015) 504–513]

Yadav, Bhagwan, Wennerberg, Krister, Aittokallio, Tero, Tang, Jing

Journal:

Computational and Structural Biotechnology Journal

Year:

2017

Language:

english

File:

PDF, 180 KB

english, 2017

47

β1 integrin promotes but is not essential for metastasis of ras-myc transformed fibroblasts

Brakebusch, Cord, Wennerberg, Krister, Krell, Hans W, Weidle, Ulrich H, Sallmyr, Annahita, Johansson, Staffan, Fässler, Reinhard

Journal:

Year:

1999

Language:

english

File:

PDF, 1.56 MB

english, 1999

48

KIFC1 is a novel potential therapeutic target for breast cancer

Li, Yonghe, Lu, Wenyan, Chen, Dongquan, Boohaker, Rebecca J, Zhai, Ling, Padmalayam, Indira, Wennerberg, Krister, Xu, Bo, Zhang, Wei

Journal:

Cancer Biology & Therapy

Year:

2015

Language:

english

File:

PDF, 702 KB

english, 2015

49

Rho and Rac Take Center Stage

Keith Burridge, Krister Wennerberg

Journal:

Year:

2004

Language:

english

File:

PDF, 335 KB

english, 2004

50

DNA microfiltration assay: a simple technique for detecting DNA damage in mammalian cells

Landerson, Per, Wennerberg, Krister, Tagesson, Christer

Journal:

Year:

1994

Language:

english

File:

PDF, 266 KB

english, 1994

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